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• 07:10, 23 June 2024 Richert talk contribs created page Quinolone DNA complexes (Created page with " '''Complexes of Quinolone Antibiotics and DNA''' Quinolone antibiotics are widely used in the clinic. They inhibit the re-sealing of the DNA after cleavage by a gyrase, thus turning a topoisomerase into a nuclease. Three-dimensional structures of covalent quinolone-DNA complexes have been elucidated by NMR and restrained molecular dynamics. '''References''' a) J. Tuma, W. H. Connors, D. H. Stitelman, C. Richert, On the Effect of Covalently Appended Quinolones on...") Tag: Visual edit