Quinolone DNA complexes: Revision history

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3 September 2024

5 August 2024

23 June 2024

  • curprev 07:1007:10, 23 June 2024Richert talk contribs 895 bytes +895 Created page with " '''Complexes of Quinolone Antibiotics and DNA''' Quinolone antibiotics are widely used in the clinic. They inhibit the re-sealing of the DNA after cleavage by a gyrase, thus turning a topoisomerase into a nuclease. Three-dimensional structures of covalent quinolone-DNA complexes have been elucidated by NMR and restrained molecular dynamics. '''References''' a) J. Tuma, W. H. Connors, D. H. Stitelman, C. Richert, On the Effect of Covalently Appended Quinolones on..." Tag: Visual edit