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- 07:03, 23 June 2024 Richert talk contribs created page Quantitative MALDI-TOF MS of Oligonucleotides (Created page with "'''Quantitative MALDI-TOF Mass Spectrometry of Oligonucleotides''' The acronym MALDI-TOF MS stands for Matrix-Assisted Laser-Desorption-Ionization Time-of-Flight Mass Spectrometry. This type of mass spectrometry was invented by Franz Hillenkamp and Michael Karas at the University of Münster. The advantage of MALDI MS is that it gives a sharp, predictable signal for a biomacromolecule, with great sensitivity and robustness to assay components like buffers. One disad...") Tag: Visual edit