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• 09:44, 23 July 2024 Richert talk contribs created page Solution-Phase Oligonucleotide Synthesis (Created page with " '''Solution-Phase Oligonucleotide Synthesis''' By far the most common way of synthesizing oligonucleotides is solid-phase synthesis. Solution-phase synthesis methods do exist, however. For example, before solid supports for the immobilization of the first nucleoside (and subsequent nucleotides during chain assembly) became available, oligonucleotides were prepared in solution. Perhaps the best-known example of this early work is Khorana's synthesis of tRNA genes. Rec...") Tag: Visual edit