Neighbor Exclusion Principle: Difference between revisions
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== | == Neighbor Exclusion Principle == | ||
The neighbor exclusion principle of classical intercalation says that between intercalation sites in a duplex one site must remain free. In other words, only every other intercalation site is occupied when classical intercalators bind to duplexes. There are numerous exceptions to this principle. | The neighbor exclusion principle of classical intercalation says that between intercalation sites in a duplex one site must remain free. In other words, only every other intercalation site is occupied when classical intercalators bind to duplexes. There are numerous exceptions to this principle. | ||
== | == References == | ||
[1] C. Robledo-Luiggi, W.D. Wilson, E. Pares, M. Vera, C.S. Martinez, D. Santiago, Partial intercalation with DNA of peptides containing two aromatic amino acids. ''Biopolymers'' '''1991''', ''31'', 907-917. https://doi.org/10.1002/bip.360310710 | [1] C. Robledo-Luiggi, W.D. Wilson, E. Pares, M. Vera, C.S. Martinez, D. Santiago, Partial intercalation with DNA of peptides containing two aromatic amino acids. ''Biopolymers'' '''1991''', ''31'', 907-917. https://doi.org/10.1002/bip.360310710 | ||
[2] M. Yousuf, I. S. Youn, J. Yun, L. Rasheed, R. Valero, G. Shi, K. S. Kim, Violation of DNA neighbor exclusion principle in RNA recognition. ''Chem. Sci''. '''2016''', ''7'', 3581-3588. https://doi.org/10.1039/C5SC03740A (Edge article) | [2] M. Yousuf, I. S. Youn, J. Yun, L. Rasheed, R. Valero, G. Shi, K. S. Kim, Violation of DNA neighbor exclusion principle in RNA recognition. ''Chem. Sci''. '''2016''', ''7'', 3581-3588. https://doi.org/10.1039/C5SC03740A (Edge article) | ||
Latest revision as of 11:41, 5 August 2024
Neighbor Exclusion Principle
The neighbor exclusion principle of classical intercalation says that between intercalation sites in a duplex one site must remain free. In other words, only every other intercalation site is occupied when classical intercalators bind to duplexes. There are numerous exceptions to this principle.
References
[1] C. Robledo-Luiggi, W.D. Wilson, E. Pares, M. Vera, C.S. Martinez, D. Santiago, Partial intercalation with DNA of peptides containing two aromatic amino acids. Biopolymers 1991, 31, 907-917. https://doi.org/10.1002/bip.360310710
[2] M. Yousuf, I. S. Youn, J. Yun, L. Rasheed, R. Valero, G. Shi, K. S. Kim, Violation of DNA neighbor exclusion principle in RNA recognition. Chem. Sci. 2016, 7, 3581-3588. https://doi.org/10.1039/C5SC03740A (Edge article)