Solution-Phase Oligonucleotide Synthesis: Revision history

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5 August 2024

23 July 2024

  • curprev 09:4409:44, 23 July 2024Richert talk contribs 1,819 bytes +1,819 Created page with " '''Solution-Phase Oligonucleotide Synthesis''' By far the most common way of synthesizing oligonucleotides is solid-phase synthesis. Solution-phase synthesis methods do exist, however. For example, before solid supports for the immobilization of the first nucleoside (and subsequent nucleotides during chain assembly) became available, oligonucleotides were prepared in solution. Perhaps the best-known example of this early work is Khorana's synthesis of tRNA genes. Rec..." Tag: Visual edit